BEMÆRK: Ansøgningsfristen er overskredet
We are seeking a highly motivated and skilled computational staff scientist to join our team in Center for Functional Genomics and Tissue Plasticity (ATLAS) for a four-year position, focusing on supporting and coordinating computational analyses on NGS data. The position is available from January 1, 2024 or as soon as possible thereafter.
ATLAS
The Center for Functional Genomics and Tissue Plasticity (ATLAS) is a Center of Excellence headed by Professor Susanne Mandrup and funded by the Danish National Research Foundation. ATLAS is hosted by the Functional Genomics & Metabolism Research Unit (FGM) at the Department of Biochemistry and Molecular Biology (BMB), SDU. ATLAS is a highly ambitious and interdisciplinary project with the overarching aim to obtain systems-level, mechanistic and cell type-resolved understanding of adipose and hepatic tissue plasticity in response to severe obesity and weight loss. The center applies a combination of functional genomics approaches, including single cell sequencing technologies, proteomics, in vivo targeting, and computational biology to study tissue plasticity in both mouse models and human biopsies.
Job Description and Role in Research Center
As a computational staff scientist in ATLAS, you will play a major role in coordinating and driving computational analyses of NGS data, in particular single cell omics data. You will be affiliated with the Mandrup group, but you will collaborate closely with experimental and computational researchers in other ATLAS research groups, including those of Associate Professor Kim Ravnskjær, Lars Grøntved and Jesper Grud Skat Madsen. In addition, to coordinating computational analyses, you will design user-friendly databases, develop semantics for metadata, develop web interface and computational pipelines for data archiving, sharing, and exploratory data analysis by the various research groups. You will train and/or assist junior researcher from bachelor students to postdocs to analyze large-scale datasets and interpret their results using state-of-the-art computational tools. You are expected to provide substantial general input to projects in our groups and help with generating high-quality representations of complex data.
Qualifications/requirements
We are looking for highly motivated and dedicated candidates with
- Documented expertise in computational biology, NGS data analysis, processing of experimental datasets, network analysis and investigation of multi-omics datasets
- Research experience within the fields of computational biology, systems biology, or bioinformatics
- Hands-on experience with NGS-related laboratory (wet lab) procedures is considered a plus
- Proficiency in relevant programming languages, e.g. Python, R, C++, Java.
- Strong background in database development: SQL, graph databases, etc.
- Experience in designing web interfaces for exploratory data analysis and data sharing
- Experience in Machine Learning would be desirable
- Passion for complex data visualization and representing data into interpretable figures
- Ideally at least one major first author publication in a relevant journal in the field
- Strong communication and collaborative skills and an interest in working in an interdisciplinary environment
- Proficiency in spoken and written English
We offer
- A Four-year staff scientist position in a stimulating and supportive, international research environment at SDU with the possibility of extension and career development for the high-performing candidate.
- Access to state-of-the-art equipment, computational facilities, and infrastructure
- Opportunity to interact with an extensive network of national and international collaborators
- A competitive salary and social benefits (health coverage, parental leave, social security etc.)
- Dedicated assistance and support with various practical, social, and legal aspects (housing, visa, administration, tax etc.), especially for international candidates through our international staff office (ISO) and department
The Mandrup Group
The Mandrup Group has a long-standing interest in understanding the molecular cross-talk between transcriptional regulation and metabolism in adipocytes and pancreatic β-cells and to understand the molecular basis for the plasticity of cells in the adipose tissue and endocrine pancreas. We also have a long-time interest in the transcriptional network regulating lineage determination and differentiation of adipocyte progenitors. Our laboratory combines genome-wide studies of factor binding, epigenetic marks, and chromatin structure with detailed molecular analyses of the crosstalk between transcriptional regulators. We run an inhouse sequencing platform including single cell sequencing and bioinformatic pipeline.
Susanne Mandrup is Director of Center of Excellence in Functional Genomics and Tissue Plasticity (ATLAS) as well as the Center of Adipocyte Signaling (ADIPOSIGN), and she heads the Functional Genomics and Metabolism Research Unit.
The Functional Genomics & Metabolism Research Unit
The Mandrup group as well as the center administration of ATLAS and ADIPOSIGN are located in the Functional Genomics & Metabolism Research Unit, at Department of Biochemistry and Molecular Biology, SDU. The research unit currently hosts eight independent research groups focusing on various aspects of functional genomics as it pertains to the regulation of cellular differentiation and metabolism. The Research Unit constitutes an international, ambitious, highly dynamic, and well-equipped working environment. The unit and the department have state-of-the-art facilities for next generation sequencing, single-cell transcriptomics, flow cytometry, mass spectrometry, metabolomics, bioimaging, and transgenic mouse work. Strategic research alliances exist with the Odense University Hospital (OUH). This means that you will be in a highly stimulating research environment with numerous opportunities for learning and developing new ideas.
Questions
For further information please contact Center Director Professor Susanne Mandrup, s.mandrup@bmb.sdu.dk.
Application deadline: November 20, 2023
Employment shall take place in accordance with the framework agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations).
Application must include cover letter, CV and certificate. All documents in connection with the application should not contain CPR number (civil registration number) – in that case, the CPR number must be crossed out.
All attached files must be in Adobe PDF format. Cover letter and CV can contain max. 5 Mb.
We recommend that you read how to apply before you apply.
The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.
INFORMATIONER OM STILLINGEN:
- Arbejdspladsen ligger i:
Odense Kommune
-Virksomheden tilbyder:
-Arbejdsgiver:
Syddansk Universitet, Campusvej, 5230 Odense M
-Ansøgning:
Ansøgningsfrist: 20-11-2023; - ansøgningsfristen er overskredet
Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5933719
